Painful Diarrhea Essentials Formula is composed of four herbs, namely Atractylodes Macrocephala, Radix Paeoniae Alba, Pericarpium Citri Reticulatae, and Fructus Anemarrhenae, and is mainly used to treat painful diarrhea caused by liver and spleen discord. In modern research, it is believed that Painful Diarrhea Essentials Formula can treat acute enteritis, chronic colitis, pediatric diarrhea, chronic diarrhea, and irritable bowel syndrome, which are all directions of its treatment. Painful Diarrhea Essentials Formula must be noted in clinical application because it can nourish the spleen and soften the liver, dispel dampness and stop diarrhea, and has a certain function of dispelling dampness when applied, so it can be applied at the discretion of people with excessive dampness. However, it should not be used for weight loss, because obesity is related to dampness, but do not use Painful Diarrhea Essentials indiscriminately, otherwise it may induce constipation.