Gallbladder cholestasis cannot be discharged by exercise, it may be caused by gallbladder stones, cholecystitis, choledocholithiasis, long-term fasting and other factors, which need to be treated with medication and surgery according to the cause of the disease. 1. Gallbladder stones: some patients will have persistent biliary colic, jaundice and other symptoms. Generally, if gallbladder stones cause cholestasis, it is considered that the gallbladder has lost its contractile function, and laparoscopic cholecystectomy should be considered. 2. Cholecystitis: common symptoms include abdominal pain, nausea and vomiting. If the pain is severe, atropine and pethidine should be used as antispasmodic and analgesic as prescribed by the doctor. If infection exists, antibiotics such as cefuroxime should be prescribed. If necessary, we need to consider cholecystectomy, percutaneous cholecystectomy and other surgical treatments. 3. Choledocholithiasis: Most patients are asymptomatic and occasionally experience abdominal pain. If acute cholangitis exists, antibiotics, such as amoxicillin and ceftriaxone, should be applied as prescribed by the doctor. Usually patients need to cooperate with the doctor to take choledochotomy, bile duct reconstruction surgery and other surgical treatment. 4. Long-term fasting: long-term fasting can be found after the gallbladder bile sludge, if the gallbladder function is good, and gradually resume eating, sludge of bile can be discharged normally. There are many reasons for gallbladder cholestasis, which need to be further examined and actively treated with the doctor.