Hib means invasive Haemophilus influenzae type b. The use of Hib vaccine is an effective measure to control Hib-invasive disease. The use of Hib vaccine is an effective measure to control invasive Hib disease. Hib vaccine has good immunogenicity and produces a good immune response after vaccination, which induces the body to produce effective protective bactericidal antibodies. Studies have confirmed that more than 95% of infants achieve protective antibody levels after the second or third dose of basic immunization, and the clinical effect is estimated to be 95% to 100%.
I. Target group of vaccination
Children from 3 months of age to 5 years of age. Vaccination can be given in any season.
II. Effects and uses
This vaccine can produce humoral immune response in the body after vaccination. It is used to prevent invasive infections (including meningitis, pneumonia, septicemia, cellulitis, arthritis, epiglottitis, etc.) caused by Haemophilus influenzae type b infection.
III. Immunization procedure and dose
1.Injections into the lateral deltoid muscle of the buttocks or upper arm.
2. Starting from 3 months of age, vaccination will be given every 1 month or 2 months, with 0.5ml each time, for a total of three times. One booster vaccination at 18 months of age.
3.Children from 6 to 12 months of age, injected every 1 month or 2 months with 0.5ml each time, for a total of two times, and booster vaccination once at 18 months.
4. For children aged 1~5 years, only one injection of 0.5ml is required.
IV. Adverse reactions
There is generally no adverse reaction after injection, but some vaccination sites have slight redness, swelling, hard knots, pressure pain, low fever or rash, which generally do not require special treatment and will subside on their own. In case of serious reactions, prompt medical treatment is required.
V. Contraindications to vaccination
1.Persons suffering from acute infectious diseases (including recovery period) and fever should suspend the injection.
2. Known allergic reactions to one of the vaccine components, especially those with a history of allergy to tetanus toxoid, serious heart disease, hypertension, liver and kidney disease are prohibited.
3. This product is limited to infants and children, and is prohibited for pregnant women.
VI. Issues to be noted in the use of Hib vaccine
1.Hib vaccine should be injected intramuscularly and can be used simultaneously with diphtheria, pertussis, tetanus, poliomyelitis, measles, mumps, rubella, pneumococcal or meningococcal vaccine, but should not be injected at the same site.
2. The same product should be used for primary and booster vaccination to produce a better antibody response.
3. Children under 2 weeks of age with Hib-invasive disease should still be vaccinated with the vaccine, because sufficient antibodies cannot be produced after natural infection in these children.