How long a 75 year old can live with acute myeloid leukemia is not generalizable, but depends mainly on the risk stratification, and is also related to the patient’s physical fitness, treatment, and the effectiveness of the treatment. If AML is left untreated, survival may be as short as 3-6 months, but if treated aggressively, survival may be prolonged accordingly, but the exact duration is uncertain and depends on the risk stratification. Risk stratification is mainly related to cytogenetic features, molecular features and FAB subtypes. Elderly people often have many underlying diseases and are not suitable for hematopoietic stem cell transplantation, and need to be treated with a combination of chemotherapy and targeted drugs. It is recommended that patients actively seek medical treatment, choose the appropriate treatment according to the doctor’s advice, and maintain a positive and optimistic mindset, which will help to improve the patient’s prognosis.