High uric acid is generally not causally related to the liver. There are two sources of high uric acid, one is excessive uric acid production and the other is impaired uric acid excretion, most of which fall into the category of impaired uric acid excretion. However, the specific pathogenesis and causes of high uric acid are not yet very clear. Some studies have shown that high uric acid may be related to a variety of factors such as genetics, diet and exercise, but is often not the effect of a single factor. The normal blood uric acid level in humans is 180-420 μmol/L, and those above 420 μmol/L are called hyperuricemia. Long-term high uric acid may lead to gouty arthritis, which is also one of the independent high-risk factors for cardiovascular disease, so it is usually better to keep blood uric acid within the normal range.