Glycite lotion does not need to be washed off after rubbing it in. Glycerite lotion is a skin medication that can be used to relieve acute itchy skin conditions such as hives or prickly heat. Glycite lotion can be protective, astringent, and anti-itching, so it usually does not need to be washed off after use. Glycerite lotion is a compound preparation, and its main ingredients are glycerite, zinc oxide, and glycerin. It can be left to settle and needs to be shaken when used so that it becomes a homogeneous suspension. This is one of the safer medications for topical use on the skin, but contact with the eyes and other mucous membranes (e.g., mouth, nose, etc.) still needs to be avoided. If you feel a burning sensation or redness at the site of application, you need to stop the medication and wash the area immediately.