Thyroid nodule hypoechoic phenomenon may consider the existence of thyroid nodules, thyroid malignant tumors and other diseases; need to be under the guidance of the doctor to carry out targeted treatment, such as regular review, drug treatment, surgical treatment, and so on. 1. Thyroid nodules: asymptomatic patients with thyroid nodules can be followed up for observation and do not need special treatment; surgery is recommended for patients with compression symptoms; patients with hyperthyroidism can be treated with drugs such as methimazole and propylthiouracil; patients with hypothyroidism can be treated with levothyroxine. 2. Malignant tumor of thyroid gland: once diagnosed as malignant tumor, surgical resection is recommended, and levothyroxine can be given to treat the tumor after surgery if necessary. Patients with hypoechoic thyroid nodules are recommended to go to the hospital and ask the doctor to make a judgment and formulate an individualized treatment plan.