High urea nitrogen and uric acid and normal creatinine are generally related to diet and exercise, and it is recommended to adjust the diet and then review. A few of them may be related to kidney damage, and further examination is recommended to clarify the diagnosis and then treat the cause. Urea nitrogen, uric acid and creatinine are the most commonly used indicators for renal function tests. Among them, the values of urea nitrogen and creatinine are greatly affected by diet, while the value of creatinine is more stable, which can accurately reflect the status of renal function. Urea nitrogen is the product of protein food decomposition and metabolism in the body. Excessive intake of protein foods, such as meat, eggs, milk intake, or protein decomposition, such as after strenuous exercise, urea nitrogen will be mildly elevated. Some diseases, such as upper gastrointestinal bleeding, extensive burns, severe trauma, and surgery can also lead to elevated urea nitrogen, and usually creatinine is not elevated at the same time. Elevated uric acid is most common in patients with gout, or after consuming large amounts of high-purine foods, such as fish, shrimp, crab and other seafood, animal liver, spinach, soy products, beer and so on. Generally speaking, when renal impairment occurs in renal disease, urea nitrogen and creatinine will be elevated, simple urea nitrogen and uric acid elevation is relatively rare, but there are a small number of cases that may be related to renal impairment, at this time, we need to further check the cystatin C and glomerular filtration rate, to clarify the diagnosis of the cause of the treatment. It is recommended that patients adjust the diet, avoid alcohol, low protein, low purine diet for 1 week after the review of renal function, such as urea nitrogen, uric acid continues to be high, need to go to the regular hospital, complete the relevant examination, clear cause, symptomatic treatment.