It is impossible to determine what medication can cure impotence and premature ejaculation. Impotence can be cured with drugs such as sildenafil, and premature ejaculation can be cured with drugs such as dapoxetine; however, medication is only one of the treatments, and there is no guarantee that it can absolutely cure these two diseases. Premature ejaculation and impotence are different types of diseases, and they are not the same medication. Patients with premature ejaculation can apply 5-hydroxytryptamine reuptake inhibitors such as dapoxetine, paroxetine and fluoxetine. Impotence can take sildenafil, tadalafil and other 5-type phosphodiesterase inhibitors. However, it is important to note that the use of medications alone does not necessarily cure impotence and premature ejaculation. There are many reasons that can lead to impotence and premature ejaculation, and there is no way to cure them simply by taking medication without eliminating the causes. Patients with impotence and premature ejaculation should go to the hospital as soon as possible, complete the relevant examinations, clarify the cause of the disease, and then choose the most appropriate treatment under the guidance of the doctor. Only in this way is a cure possible.