Glucose plus potassium chloride injection can usually be used to treat hypokalemia. If the patient has hypokalemia, it has a great impact on the patient’s body, and the patient may have clinical manifestations such as peripheral weakness, muscle weakness, abdominal distension and cardiac arrhythmia. So after the appearance of hypokalemia should be corrected in time, and glucose plus potassium chloride injection is a method to correct hypokalemia in time. There are many causes of hypokalemia, common ones are insufficient food intake, vomiting, diarrhea, application of potassium-excreting diuretics, hypokalemic familial periodic paralysis, long-term application of glucocorticoids, etc., which may cause hypokalemia. When patients have hypokalemia, they should be treated with potassium supplementation in time. Mild hypokalemia can be treated with oral high potassium food as well as oral potassium chloride tablets, while severe hypokalemia requires intravenous potassium supplementation, such as intravenous glucose plus potassium chloride injection. Potassium supplementation needs to be administered under the guidance of a doctor, and the blood potassium index needs to be monitored at the same time in order to have safe and effective potassium supplementation treatment.