Introduction：Winter has come again, and the haze alarm is sounding again. All kinds of news about the haze and lung cancer is endless, what Beijing lung cancer incidence rate rose 40% in 10 years, the incidence of female lung cancer continued to rise for 33 years, lung cancer jumped over breast cancer to become the first female high incidence of cancer, the number of lung cancer patients in our country is more than accounted for the world’s 1/3 more …… then the relationship between lung cancer and haze has been clear! The Lung Cancer Is it possible to conduct early screening for lung cancer? This is a question of great concern to everyone. Does everyone need to be screened? Not really! Some people may ask, “The haze is so terrible, does everyone need to be screened for lung cancer?” There is no need to be so hasty. 1, a survey shows that even in high-risk groups for lung cancer screening, the detection rate of lung nodules is 24.2%, but in the end, it was confirmed that 96.4% of these nodules have nothing to do with lung cancer (known as false positives in medicine). In the general population, the false positive rate will be even higher. 2. It takes 2 to 3 years of observation for a suspected patient to be screened before a final answer is given, which not only causes great panic to the patient and his family, but is also a waste of medical resources. 3. Although the radiation dose of low-dose spiral CT used for screening is relatively low, it does not mean that there is no radiation at all. If you are not a high-risk group of lung cancer, it is unnecessary to be exposed to this radiation. People with long-term exposure to cigarettes, haze, and oil smoke should be screened! So let’s talk about who exactly belongs to the high-risk group for lung cancer and is in need of screening. At present, there is not a large-scale survey and research in China, so the following content is just the current situation in the country combined with the content of the U.S. guidelines, deduced that should be done for lung cancer screening of the population. Mandatory screening population Age 55-74 Smoking history >30 pack-years (pack-years: multiplying the number of packs per day and the number of years of smoking, e.g., one pack a day for 30 years or two packs a day for 15 years) Smoking cessation for <15 years High-risk population: (Recommended screening population) Age >40 years old (including any of the following risk factors) Smoking for ≥20 packs of cigarettes; history of secondhand smoke; family history of lung cancer; history of other neoplasms; history of lung cancer; history of lung cancer; history of other tumors; history of lung cancer; history of lung cancer; history of secondhand smoke; history of lung cancer; history of lung cancer; history of lung cancer; history of lung cancer. Family history of lung cancer; History of other tumors; Suffering from pulmonary fibrosis and chronic obstructive pulmonary disease; Long-term outdoor exercise in cities with severe haze; Long-term exposure to oil smoke. It is recommended that the above people should have a low-dose spiral CT screening for lung cancer once a year. The best way to screen for lung cancer, look here! Here we will talk about what is low-dose spiral CT. low-dose spiral CT can effectively detect small nodules in the lungs smaller than 1 cm, which is more suitable for the early screening of lung cancer. Some people may ask if it’s okay to take X-rays. The answer is – no. A study proved that 53,454 residents aged between 55-74 years old were screened with low-dose spiral CT and X-ray at the same time, and the detection rate of CT was 24.2%, which means that nearly 1/4 of the so-called normal people found nodules in the lungs, while the detection rate of X-ray was only 7%. In comparison with CT, nearly 20% of those detected by X-ray were found to be unrelated to lung cancer. The radiation dose of low-dose spiral CT is 1/4 of that of conventional CT, and for people at high risk of lung cancer, the risk of developing lung cancer is much greater compared to the risk of this radiation. Blood drawn for tumor markers, exploring! Many people have heard of tumor markers, which are metabolites of tumors that are released into the bloodstream, and we can infer the presence of tumors through blood tests. However, unfortunately, no type of tumor marker has been found that is effective for lung cancer screening. Genetic prediction of lung cancer to be researched! You may be aware of a very hot news a few years ago, when a foreign movie star had her breasts and ovaries removed prophylactically based on genetic prediction. In the field of lung cancer, the academic world has not recognized the matter of gene prediction of cancer, and its feasibility and accuracy are yet to be studied. In China, the sputum test for lung cancer-related gene mutations is underway, and we hope to establish a standard for China’s high-risk group for lung cancer based on big data as soon as possible.