Diclofenac Sodium Extended-Release Tablets is one of the commonly used NSAIDs with anti-inflammatory and analgesic properties, reducing swelling and fever. Diclofenac Sodium Extended-Release Tablets can provide anti-inflammatory and analgesic effects mainly by inhibiting the conversion of arachidonic acid to prostaglandins, thus reducing the production of prostaglandins. Diclofenac sodium extended-release tablets are mainly used for the treatment of acute and chronic rheumatoid arthritis, acute and chronic ankylosing spondylitis and osteoarthritis, and can also be used for the treatment of frozen shoulder, myofasciitis, low back pain, sprains and strains, and other soft tissue injuries. The drug is also used for acute gout, dysmenorrhea or adnexitis, toothache or postoperative pain relief. It can also be used for post-traumatic pain inflammation, such as the treatment of sprains and strains, and severe infections pain and inflammation in ENT, such as tonsillitis and sinusitis, can be used in this regard. However, it is important to note that some patients taking diclofenac sodium extended-release tablets may experience adverse reactions such as epigastric pain, nausea or vomiting, and in severe cases, may also lead to stomach bleeding. It is contraindicated in people with known allergy to the product; in people with asthma, urticaria or allergic reactions induced by taking aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs); in people with perioperative pain in coronary artery bypass grafting (CABG); and in people with history of gastrointestinal bleeding or perforation after the application of NSAIDs. The medication should be taken in strict accordance with the doctor’s instructions and should not be used without authorization.