The age between 38 and 42 years old is possible to have a second child, and there is no such thing as good or bad. At present, with the opening of the two-child policy, a lot of families are beginning to consider having a second child. 38-42-year-old women are older, ovarian function gradually tends to decline, the chances of chromosomal aberrations in the egg increase, which is prone to cause miscarriage, stillbirth or deformity. Therefore, couples who are ready to get pregnant at this age must do a good pre-pregnancy checkup to see if there is any abnormality in the general condition, blood pressure, blood sugar, uterine attachments, and the function of various organs, and make a comprehensive assessment. Before getting pregnant, it is important to find out if there are any underlying medical conditions, and if there are any abnormalities, early treatment should be given. In addition, the whole process of pregnancy must be standardized obstetric examination, do not be careless, early detection of maternal and fetal complications during pregnancy, and give timely treatment.