Wake up dry mouth may be caused by improper temperature and humidity, may also be due to dry syndrome, diabetes and other diseases. 1. Improper temperature and humidity: If you sleep in a high temperature, low humidity environment, it is easy to wake up with a dry mouth, which is a normal physiological phenomenon. 2. Dry syndrome: the etiology of this disease is not clear, may be related to viral infections, genetics, immune dysfunction and other factors, the patient’s mouth, eyes, nose and other parts of the mucous membrane secretion is reduced, so some patients will wake up with dry mouth and tongue symptoms, but also dry eyes, tongue pain and other symptoms. 3. Diabetes: Studies have shown that the occurrence of diabetes is the result of a combination of genetic and environmental factors, including over-nutrition and aging. Patients will have symptoms such as excessive drinking, excessive urination, and excessive eating, so there may be a performance of waking up with a dry mouth. In addition, waking up with dry mouth may also be caused by hypokalemia, uremia, upper respiratory tract infection and other diseases. If waking up with dry mouth is excluded due to physiological factors, it is necessary to go to the hospital in time to consult a doctor to clarify the cause of the disease.