The effects of men’s smoking on pregnancy preparation include decreased sperm quality, lower conception rate, and increased fetal malformation rate. The reason why men’s smoking affects pregnancy preparation is that tobacco contains a variety of harmful substances, including nicotine, carbon monoxide, tar, and a variety of carcinogens. These harmful substances may affect sperm vitality, count, morphology, and survival rate, in addition to testosterone production, which affects spermatogenesis. This may therefore lead to difficulties in conception, fetal malformations, and other conditions. When preparing for conception, men should quit smoking and limiting alcohol 3 months in advance, exercise and eat healthily, and are advised to undergo checkups in advance to ensure their reproductive health. In addition, men who have been smoking for a long time should go to the hospital to check the semen routine, and if there is any abnormality, they should be adjusted under the guidance of the doctor.