Blood sperm is both the name and symptom of Chinese medicine, the earliest discussion of this disease is found in the Sui Dynasty Chao Yuanfang’s “Treatise on the Origin of Diseases”, which said: “The kidney collects sperm, sperm, the blood is also made. The deficiency of the kidneys is so weak that it cannot store essence, so the essence and blood are all out”. Blood sperm can occur in any segment of adult males, but is particularly common in middle-aged and young adults. The main manifestation is blood in the semen, which may be accompanied by frequent urination, urgent urination and painful urination. In mild cases, only red cells in the semen are found through microscopic examination, while in severe cases, blood in the semen is visible to the naked eye, also known as “hematospermia”. Hemospermia is most commonly seen in patients with modern medicine’s vesiculitis. From the anatomical location of the seminal vesicles, it is close to the prostate, vas deferens, bladder, etc. Therefore, seminal vesiculitis is often secondary to inflammation of the urinary tract or reproductive system and other adjacent organs, with three routes of infection: upstream infection, bloodstream infection and lymphatic infection. The diagnosis of this disease is relatively easy, but other pathologies such as seminal vesicle cancer and hematological system must be excluded. At present, Western medicine treats hematospermia mainly with antibiotics, and in severe cases with some hemostatic drugs, but the efficacy is not very precise. In Chinese medicine, it is believed that sperm is hidden in the sperm chamber, and the main cause of bleeding in the sperm chamber is heat entering the sperm chamber, damaging the blood channels, forcing the blood to move delicately, and the blood coming out with the sperm; or siltation and defeat of sperm stopping inside the sperm chamber, blocking the blood channels, and the blood not following the meridians; or deficiency of spleen and kidney qi, which cannot control the blood, and the blood and sperm coming out together. Clinical treatment is divided into four types: damp-heat injection type, yin deficiency and fire type, spleen and kidney deficiency type, and blood stasis and obstruction type. The treatment of blood sperm in Chinese medicine is mostly based on “blood”, using cooling blood to stop bleeding, nourishing blood to stop bleeding, nourishing qi to stop bleeding, activating blood to stop bleeding, etc. Then, according to the different treatment methods of damp-heat, yin deficiency, spleen and kidney deficiency, blood stasis, etc., together with clearing heat and relieving dampness, nourishing yin and lowering fire, benefiting kidney and nourishing spleen, etc., and then using this prescription can often receive good results. The advantage of TCM in the treatment of hematospermia is the flexibility and diversity of drugs and the diversity of mechanisms and targets of action. For example, modern pharmacological research proves that the heat-clearing and blood-cooling drugs can inhibit the inflammatory reaction and enhance the function of phagocytes; the blood-activating drugs can improve the permeability of capillaries and promote the repair of damaged tissues and cell regeneration; the deficiency-supplementing drugs can enhance the non-specific resistance of the organism to harmful stimuli, etc. Thus, it is evident that the effect of herbal compound treatment of hematospermia is significantly better than that of simple application of antibiotics is based on scientific basis. In October 2008, Chen, 23 years old, suffered from seminal vesiculitis for more than 1 year, successively transferred to Nanning, Hechi, Liuzhou and other places, treated by many hospitals, spending more than 20,000 yuan, but Xiao Chen’s disease has not improved, causing a great impact on his spirit, almost lost confidence in treatment. However, it was a great honor for Dr. Shen to meet him. After patiently inquiring about his condition and treatment, Dr. Shen analyzed his diagnosis of hematospermia, which is a type of qi stagnation and blood stasis, and treated him with Blood Loss Wonderful Formula plus reduction for more than 2 months, and he was cured. Treatment for hematospermia: actively seek medical advice, eliminate tension; abstain from sexual desire, avoid excessive sexual stimulation; pay attention to hygiene, and eat less spicy and hot products.