Betamethasone valerate is mainly used externally for dermatitis, allergy and all kinds of eczema, and neomycin skin cream is generally used for skin infections related to skin diseases can treat dermatitis, allergies and other skin diseases. 1. Betamethasone valerate is mainly used for skin inflammation of topical drugs, belongs to the hormone drugs, acne has a certain efficacy, mainly used for eczema, dermatitis and other skin diseases, treatment of adrenocorticotropic hormone sensitive dermatitis. Belonging to the glucocorticoid drug, the disease is accompanied by the bacteria sensitive to penicillin or penicillin-sensitive bacteria triggered by the dual infection, but pay attention to the control of the frequency of use, the long-term use of the side effects of the relatively large. 2. Neomycin Skin Cream is effective in treating acne with infection; it is mainly used to kill gram-positive cocci on the surface of the skin; clinically, it is mainly used for treating bacterial infectious skin diseases; for example, impetigo, folliculitis, etc., and it can also be used for secondary infections caused by other diseases. However, it should be noted that it should not be applied to patients with a history of allergy to any of the components of the drug, topical corticosteroids can have side effects that occur with the systemic use of corticosteroids, including adrenal inhibitors, and care should be taken when using it, especially in infants and children, to avoid the use of neomycin on open wounds or damaged skin, in addition to the fact that it should not be used in large quantities for long periods of time in pregnant women. When using medication, it is important to follow the doctor’s instructions, rational application of drugs, do not arbitrarily use drugs to avoid causing serious side effects as well as adverse reactions.