The cost of treatment for Lupus erythematosus varies greatly, ranging from hundreds to tens of thousands of dollars per month, depending on the type, age and condition of the patient. Lupus erythematosus is categorized into cutaneous and systemic lupus erythematosus, and patients of different types, ages and conditions require different treatment plans. Cutaneous lupus erythematosus is usually confined to the skin, while systemic lupus erythematosus can have damage to different organs, so the cost of the former is generally lower than the latter. Older patients are more complex and prone to complications, and are generally more expensive. Patients with relatively mild disease are treated with anti-malarials and non-steroidal anti-inflammatory drugs (NSAIDs), which cost about $100 to $1,000 per month. If the condition worsens, relatively expensive drugs or treatments may be used, such as biologics, immunosuppressants, immunoglobulin and other drugs, immunosorbent, plasma exchange and other treatments, which may cost 5,000 to 10,000 yuan per month. In addition, other costs may be incurred in case of serious complications such as lupus nephritis, hemolysis, lupus encephalopathy, alveolar hemorrhage, etc., or when the patient’s condition requires resuscitation. It is recommended that patients with lupus erythematosus visit a rheumatologist in a timely manner and follow the doctor’s instructions.