There are many reasons for the blisters on the hands, may be due to contact dermatitis, sweat herpes, ringworm and other reasons, according to the specific circumstances of the use of drugs to treat the symptoms. 1. contact dermatitis: for the skin contact with external substances triggered by inflammatory skin diseases, can appear on the hands of small blisters symptoms, treatment can be oral antihistamines such as loratadine, or external glucocorticoids such as hydrocortisone ointment. 2. Sweat herpes: a special type of hand eczema. Itching or burning sensation of varying degrees can be self-conscious. Glucocorticosteroids such as mometasone furoate can be used externally, and those with much exudation can use 3% boric acid solution or 0.1% isacridine solution to disinfect, anti-inflammatory and astringent cold wet compresses. 3. Ringworm: If the hand skin is infected by pathogenic fungi, it will lead to ringworm, mostly manifested as erythema and small blisters, can be under the guidance of a doctor, the use of naftifine ketoconazole cream and other drugs to ease the daily need to keep the hands clean, to avoid the use of shared hygiene products. All of the above medications should be used in accordance with medical advice. There are many reasons for the blisters on the hands, it is recommended to go to the hospital in time, to clarify the cause of the disease, symptomatic treatment.