Loratadine can be taken for allergy-induced vulvar itching, but it is not recommended for other causes of vulvar itching. Loratadine is an antihistamine drug that mainly relieves and treats allergic diseases. If it is due to contact with irritating chemicals or allergy to the material of underwear, you can take loratadine orally to relieve the itching symptoms in this case. However, many diseases can lead to vulvar itching, such as vulvar leukoplakia, vaginitis, etc., this situation is the need for disease-specific use of appropriate drugs for treatment, such as vulvar leukoplakia can be applied locally fluoride easy cream, tretinoin ointment, etc.; vaginitis can be used to metronidazole suppositories, clindamycin ointment, etc.. Loratadine may have some adverse reactions, such as fatigue, headache, drowsiness, dry mouth, nausea, rash, etc. Occasionally, there may be visual blurring, lower or higher blood pressure, tachycardia, jaundice, etc., so it should be used under the guidance of a doctor, and should not be blindly self-administered, so as to avoid adverse effects.