First-aid drugs for respiratory failure are as follows: 1. The commonly used first-aid drugs for respiratory failure in clinical practice are respiratory stimulants, including drugs such as niclosamide and naloxone, but there are indications for their use, mainly for respiratory paralysis caused by abnormalities in the respiratory central chemoreceptors; 2. Drugs of theophylline type, which are mainly used for treatment through the effect of airway dilation; 3. Drugs to release tracheal spasm and promote sputum excretion, such as such as salbutamol, budesonide, mucosolvan, etc., can be used in the treatment of respiratory failure. If drug therapy is ineffective or poorly effective, early treatment such as tracheal intubation and airway patency should be performed.