Cough variant asthma, severe pneumonia, cardiac insufficiency can occur at night cough, when the patient has a cough at night, it is recommended to actively seek medical attention, improve the relevant examination, a clear diagnosis of different diseases clinical treatment is different: 1, if the patient is due to cardiac insufficiency and the occurrence of nocturnal cough, according to the electrocardiogram, blood pressure, heart rate to take the cardiac, diuretic, vasodilator treatment, the commonly used drugs, including Digoxin, sildenafil, furosemide, nitroglycerin, sodium nitroprusside, etc. 2, if the patient is due to cough variant asthma and the night cough, oral montelukast sodium, inhalation of XinBiKe or ShuLiDi. 3, if the patient is due to severe pneumonia and the night cough, need to carry on the active anti-infective treatment, and at the same time, if the patient’s cough is more serious, can be taken by mouth to stop coughing drugs.