LDL cholesterol is high at 4.5, requiring dietary control, low-fat diet, appropriate exercise, and lifestyle improvement. Combined with the patient’s risk stratification for cardiovascular disease, lipid-lowering goals are set, and statin drugs such as atorvastatin are given to control blood lipids. LDL cholesterol 4.5, which is diagnostic of hypercholesterolemia, is a type of hyperlipidemia, and the patient needs to have a low-fat diet and eat less high cholesterol foods such as fried foods and animal offal. Increase consumption through appropriate exercise to help control blood lipids. Different groups of people have different lipid-lowering goals, for example, people without other diseases are at low risk of cardiovascular disease, and LDL is required to be lower than 3.4; people with previous myocardial infarction or coronary stent implantation belong to the group at very high risk of cardiovascular disease, and LDL is required to be lower than 1.8. If the control of diet and exercise do not meet the standard of lipid control, lipid-lowering drugs need to be added. Lipid-lowering drugs to reduce cholesterol are statins, such as atorvastatin, resuvastatin, pitavastatin and so on. If lipid control is not achieved despite oral statin medication, it is recommended to add ezetimibe orally. If still not up to standard, there are also injections to enhance lipid lowering, such as eloxitumomab injection. In order to reduce the risk of cardiovascular events, it is recommended to formally consult the cardiology department for lipid-lowering treatment under the guidance of specialized doctors.