The amount of Metformin Extended-Release Tablets to be taken in a day varies depending on the condition, and the exact dosage needs to be consulted with a medical professional. The instructions recommend a starting dose of 500mg of Metformin Extended-Release Tablets to be taken 1 time/day with dinner. The dose is increased by 500mg every week, and the maximum dose is 2000mg once/day with dinner. If blood glucose is not satisfactorily controlled with 2000mg 1 time/day, consider switching to 1000mg 2 times/day with meals. If a larger dose of metformin is also needed, the maximum dose of 2550mg/day of metformin hydrochloride tablets should be used, taken in divided doses. It should be noted that, for the taking of drugs, it is recommended to strictly follow the doctor’s instructions to avoid self-adjustment of the dosage of the drug, resulting in adverse reactions after the use of the drug.