Retinoic acid cream is a topical preparation of a derivative of vitamin A. The main effect of this drug is an anti-proliferative effect, and it also has a certain keratolytic effect, and its low concentration preparation has a certain keratinizing effect, so the clinical application of vitamin A cream is actually very wide. It can be used for acne, especially common acne, and closed acne. It is also useful for flat warts and some keratotic skin diseases, such as palmoplantar keratosis or periorbicular keratosis. A low concentration of retinoic acid cream can be used for some facial keratin exfoliation that is more pronounced and can promote keratin formation to some extent.