Pain in the cheeks after drinking alcohol may be due to oral ulcers, mumps, pulpitis and other causes, need to take general treatment, metronidazole and other medications. 1. Mouth ulcers: because alcohol has a strong stimulating effect on the oral mucosa, so may be triggered after drinking mouth ulcers acute attack, located in the cheek area of the ulcers can be caused by the cheeks, you can use chlorhexidine gargle, at the same time can be appropriate oral B vitamins, especially vitamin B2 , B6, etc. to repair the oral mucosa. 2. Mumps: It can also cause pain in the cheeks, which can be easily induced or aggravated after drinking. Eat fluids or semi-fluids, avoid acidic foods. Antiviral drugs such as ribavirin can be used, and anti-inflammatory drugs such as cefixime can be used if combined with bacterial infection. 3. Pulpitis: It triggers tooth pain and can radiate to the parotid gland and other parts of the body, and is also an important cause of pain in the cheeks after drinking. You can use anti-inflammatory drugs such as metronidazole, and need stomatological treatment, filling or root canal treatment, or even extraction of the tooth. There are other causes of pain in the cheeks after drinking wine, it is recommended to consult a doctor in time to identify the cause of the disease, the cause of the treatment, the above medication as prescribed by the doctor.