Neuron-specific enolase high 30.50 is abnormal (high as hell) and its increase is positively correlated with the severity of the disease. Neuron-specific enolase is a tumor marker, and the normal value of neuron-specific enolase is in the range of 15 ng/ml; if it is more than 10% of the normal value, it needs to be taken seriously. Thus, a high neuron-specific enolase of 30.50 is abnormal. Elevated neuron-specific enolase is often indicative of malignant tumors originating from neural tissue or the neuroendocrine system, such as neuroblastoma, small cell lung cancer, pheochromocytoma, medullary carcinoma of the thyroid, and pancreatic islet cell tumor. Usually, a significant increase in the level of this enzyme is positively correlated with the severity of the disease, and the change of this index before and after treatment is often used to observe the effect of treatment. If the physical examination reveals that the neuron-specific enolase level is obviously elevated, it is necessary to go to the hospital and listen to the advice of specialists, and actively carry out relevant examinations to clarify the cause, so as to avoid delaying the condition, which may lead to serious consequences.