Need to clarify the reason why menstruation does not come for more than 40 days, may be endocrine disorders, pregnancy, polycystic ovary syndrome, etc., if the endocrine disorders should improve the bad habits, pregnancy needs to be examined by a doctor, polycystic ovary syndrome can be taken to ethinyl estradiol cyclopropylprogesterone tablets, dieldieldieldrin tablets and other medications. 1. Endocrine disorders: may be affected by emotional stress, late at night and other factors, caused by female endocrine disorders, resulting in irregular menstruation, menstruation more than 40 days do not come phenomenon, usually should pay attention to maintain a good state of mind, avoid staying up late, to ensure that sufficient rest and sleep, can help improve. 2. Pregnancy: menopause is a typical manifestation of pregnancy, menstruation that does not come for more than 40 days may be pregnant, if accompanied by nausea, fatigue and other symptoms, it is recommended to consult a doctor for ultrasonography, if pregnant, pay attention to rest and nutritional intake, and regular obstetrics examination. 3. Polycystic ovary syndrome: it can lead to irregular menstruation, infertility, obesity and other symptoms, which can cause menstruation for more than 40 days not to come, you can take ethinyl estradiol cyproterone tablets, dydrogesterone tablets, etc., but pay attention to the serious liver dysfunction, or have a history of serious liver disease is prohibited, the emergence of breast pain, nausea, abdominal pain, and other adverse reactions to need to stop the drug immediately. In addition to the above reasons, there may be other reasons for not having a period for more than 40 days, it is recommended to consult a doctor in a timely manner, according to the specific circumstances of the appropriate treatment, the medication must be taken in accordance with the doctor’s instructions.