The differences between cephalosporin and roxithromycin are mainly different types, different antibacterial spectrums and different skin test requirements.
1. Different types: Cephalosporins belong to the β-lactam class, which are bactericidal agents that mainly inhibit cell wall synthesis, thus leading to bacterial edema and lysis. Roxithromycin, on the other hand, belongs to macrolide antibiotics, which are bacteriostatic agents, mainly inhibiting bacterial protein synthesis.
2. Antibacterial spectrum is different: Roxithromycin on common gram-positive cocci, atypical pathogens, such as Mycoplasma pneumoniae, Chlamydia, and Legionella pneumophila healing effect is very good; and cephalosporins are poor for the efficacy of these bacteria.
Cephalosporins are more effective against gram-positive cocci and can be used for respiratory tract infections, abdominal infections, urinary tract infections, and soft tissue skin infections. Third-generation and fourth-generation cephalosporins are effective against gram-negative bacilli, including Pseudomonas aeruginosa, while roxithromycin is not effective against this genus.
3. Skin test requirements are not the same: roxithromycin does not need to do skin test; and cephalosporins need to ask whether there is a history of allergy before use, and also need to do skin test.
Although cephalosporin and erythromycin are both anti-inflammatory drugs, but the use of different objects, so you need to be in the face of the doctor’s guidance under the correct use, not blindly take on their own.