Chronic atrophic gastritis combined with severe atypical hyperplasia should be highly guarded against cancer and surgical treatment can be considered. Intestinalization should also be given attention, so what exactly is intestinalization and what is atypical hyperplasia? First of all, it should be clear that enterosis and atypical hyperplasia are two pathological concepts that must be diagnosed under the microscope by a professional through pathological biopsy.
Intestinalization, also known as intestinal glandular hyperplasia, is a pathological change in which the gastric mucosa is replaced by the intestinal mucosal epithelium under the long-term repeated stimulation of chronic inflammation and various harmful factors.
Atypical hyperplasia, also known as heterogeneous hyperplasia, also occurs when the epithelial cells of the gastric mucosa are proliferated or intestinalized under the long-term repeated stimulation of chronic inflammation and various harmful factors. This pathological phenomenon is called atypical hyperplasia. Atypical hyperplasia is a more serious pathological change than intestinalization, which can develop directly from chronic atrophic gastritis or through intestinalization, and is a stage that chronic atrophic gastritis must go through to develop into gastric cancer.