Large red and swollen pimples may be formed due to inflammatory acne or folliculitis. It is recommended that patients take oral medication, topical medication, or physical therapy to improve the condition after clarifying the specific cause of the condition under the guidance of a doctor. 1. Inflammatory acne: patients can use topical benzoyl peroxide and adapalene gel to improve. At the same time, doxycycline hydrochloride and minocycline hydrochloride can be taken orally, and patients can also be treated by photodynamic therapy with LED red light irradiation. 2. Folliculitis: Folliculitis is a kind of purulent skin inflammation, and can be treated with topical antibiotic drugs, such as mupirocin ointment and fusidic acid ointment. In severe cases, anti-inflammatory drugs such as cephalosporins and metronidazole can also be taken orally. For the existence of red, swollen and large acne patients, it is recommended to promptly go to a regular hospital for examination and standardized treatment under the guidance of a professional doctor.