Initial symptoms of leukemia include bleeding, anemia, infection, etc., which are respectively caused by platelet reduction, hematopoietic abnormality and chronic hemorrhage, and lowered immunity. 1. Bleeding: mainly caused by abnormal coagulation function. Platelet count of leukemia patients is easy to decrease, which causes the decrease of coagulation function, thus easy to bleed, such as skin purpura, nosebleed and so on. 2. Anemia: Bone marrow hematopoietic abnormality in leukemia patients can cause abnormal proliferation or reduction of red blood cells, thus causing anemia; or patients with long-term chronic bleeding, etc., can also cause anemia. 3. Infection: As the immunity of leukemia patients is lowered, long-term chemotherapy causes a further decline in immunity, which can easily lead to infections, such as lung infections. Some patients may also have enlarged lymph nodes, liver and spleen at early stage, which is mainly caused by infiltration of leukemia cells. If the above symptoms occur, it is recommended to go to the hospital in time, can be under the guidance of physicians through “early detection, early diagnosis, early treatment” to reduce the adverse effects of the disease, it is recommended that the patient to establish confidence in the treatment.