The more you rub your hands at night, the more itchy they get, the more itchy they may be due to urticaria, contact dermatitis, insect bite dermatitis, pruritus and other causes. 1. Urticaria: is a temporary increase in vascular permeability of the skin mucosa, resulting in limited edema, can cause wind, itching, may lead to itchy hands at night the more you rub the more itchy. 2. Contact dermatitis: hands in contact with sensitizing or irritating substances, caused by allergic or irritating reactions, may lead to nighttime itchy hands the more you rub the more itchy phenomenon. 3. Insect bite dermatitis: insect bite dermatitis on the hands caused by mosquito bites can also cause swelling and itching, resulting in itchy hands at night the more you rub the more itchy. 4. Pruritus: complex etiology, manifested as general or local itching, can also lead to the phenomenon of itchy hands at night the more you rub the more itchy. Itchy hands at night, there may be other reasons, you need to go to the hospital to check, clear cause.