The normal range of alanine aminotransferase is generally standardized at 40 U/L. The normal value varies slightly from hospital to hospital depending on the instrument reagents. Whether the result is normal or not depends on the normal range of the specific report. In a patient with a high glutamate transaminase, it is relatively significant, while a low one basically does not have much clinical significance. If it is high, it is mainly considered that some liver diseases cause abnormal liver function. The main and most common diseases include viral hepatitis, various types of cirrhosis, intra- and extra-hepatic bile duct stones, and benign and malignant occupations of the liver. The specific diagnosis should be combined with the patient’s clinical manifestations and other examinations, including hepatitis B two-to-one DNA test, hepatobiliary ultrasound and imaging examination, etc. to clearly take targeted treatment.