A pustule on the face is mainly seen in skin boils and may also be associated with cystic acne, which in terms of treatment is mainly eliminated by anti-inflammation. 1. Skin boils. Skin boils are inflammatory skin diseases that occur deep within the hair follicles and are treated with oral and topical medications such as oral amoxicillin capsules, topical ichthyosin ointment, mupirocin ointment, and so on. 2. Cystic acne. Cystic acne is a more serious type of acne, choose anti-inflammatory drug treatment, commonly used anti-inflammatory drugs such as doxycycline hydrochloride tablets, clarithromycin capsules, etc., can be supplemented with the use of intradermal steroid hormone injections. Surgery is generally not recommended for pustules on the face to avoid scarring. If necessary, you need to consult a doctor and choose the appropriate way according to the severity of the disease.