Cervical cancer is a common gynecologic malignancy, second only to breast cancer, and its incidence is gradually becoming younger in recent years. Cervical intraepithelial neoplasia (CIN) consists of atypical hyperplasia and carcinoma in situ, and is a group of precancerous lesions closely related to cervical infiltrative carcinoma. There are two outcomes: either the lesions regress spontaneously or they develop into invasive cancer. If left untreated, it will become cancerous after a period of time (3-8 years on average). Aggressive and effective management of CIN can interrupt the course of the disease and prevent the development of cervical cancer. Cervical LEEP conization is one of the common methods to diagnose and treat CIN. Indications 1.Colposcopic biopsy diagnosis of CIN grade II and CIN grade III usually requires conization for comprehensive evaluation or as treatment. 2.Colposcopy biopsy diagnosis of CINI grade, HPV high risk positive, those who have given birth, and patients with psychological burden requiring treatment. 3.For those with colposcopic biopsy report of carcinoma in situ, not excluding infiltration or the depth of infiltration is unclear, it is more important to determine the depth of infiltration through conization. Preoperative preparation 1. Time: 3-7 days after menstruation, or 2-3 days after menstruation if the menstrual period is short. 2, there is no time limit for menopausal women. 3, there is a contraceptive ring tail wire first take the ring. 4, recent history of childbirth after 3 months after delivery, 2 months after the history of abortion, scraping and other uterine operation history after 1 month. 5.Check the white belt routine to exclude trichomonas and mycobacteria, if there are abnormalities first treatment. 6.Blood routine, coagulation four items. Postoperative observation 1. 5-7 d after surgery, the vaginal discharge increases slightly and is yellowish or light red. 7-10 d after cervical debridement, there is a little bleeding, which lasts for about 10 days. Yunnan Baiyao can be applied to the cervical wound to stop bleeding. 2.Post-operative follow-up CIN patients can see complete repair of the cervix with smooth appearance and return to natural state after 6-8 weeks post-operative review. Postoperative follow-up 1. 2 months after the operation, we must review once a month to record the wound repair, vaginal bleeding and discharge. 2. Review at the 3rd, 6th and 12th month. 3. The second year, the examination should be done once every six months. 4. Every time TCT+HPV examination is performed, patients with abnormalities are biopsied, normal cervical cytology or normal colposcopy is determined as normal follow-up, no CIN lesion exists within six months after treatment is considered as cure, CIN lesion is found to exist within six months as lesion persists, CIN lesion is found to be recurrence after one year of treatment. LEEP surgery advantages 1, LEEP surgery using high-frequency electric knife, in contact with the body instantly since the tissue itself generates impedance, absorbing electric waves to generate high heat, to achieve a variety of cutting hemostasis purposes. leep surgery compared with the traditional cold knife can achieve the fine surgical results of the traditional cold knife can not reach, and can provide a complete specimen of non-carbonized tissue, the edge of the tissue does not hinder the pathological examination, small damage to adjacent tissues. Therefore, it has largely replaced cold knife conization. 2, LEEP surgery has the advantages of less intraoperative bleeding, simple operation and fast recovery after surgery. 3, It is a blessing for young and childless patients with CIN grade III cervix because LEEP knife can preserve the uterus and reproductive function. Regarding the impact of the LEEP procedure on the pregnancy situation, studies have found that women with a history of cervical LEEP surgery have a higher incidence of prolonged first stage of labor, cesarean section rate and cervical laceration in labor. This must be communicated with the obstetrician at the time of delivery.