Herpes zoster usually peaks 3-4 days after the onset of the disease, with the most severe lesions and painful symptoms. Herpes zoster is characterized by flaky erythematous patches, clusters of mung bean to soybean sized blisters, or in severe cases, hemorrhagic blisters, or pustules when combined with bacterial infection, accompanied by significant nerve pain in the form of paroxysmal pinpricks, especially at night. In most patients, the typical skin lesions are accompanied by obvious neuropathic pain, with the lesions and pain symptoms peaking in 3-4 days and the rash slowly crusting off in 5-7 days, and the neuropathic pain begins to improve. Occasionally, a small number of patients may develop symptoms of neuralgia before the appearance of lesions. Such patients are often easily misdiagnosed with other pain-causing diseases, such as acute appendicitis, before the appearance of typical skin lesions. When symptoms of herpes zoster appear, patients are advised to seek timely treatment at a dermatologist to avoid delays.