Itch is closely related to visceral malignant tumors Foreign medical literature elaborates that itch is closely related to visceral malignant tumors. The reason for this is unknown, but experts speculate that the tumor cells may produce histamine and some bioactive substances, which will stimulate the sensory nerve endings of the skin after reaching the skin with blood circulation, causing itchy skin to varying degrees, especially at the early stage of the disease. Data show that 16%-30% of elderly people with malignant lymphoma, 25% of patients with malignant tumors of genital organs, 25%-60% of elderly women with cancer, and 50% of patients with malignant tumors of the rectum will have different degrees of itchy skin. What is the difference between cancer itch and ordinary itch The itch caused by cancer is different from ordinary itch. It is characterized by: no history of itching in general but suddenly occurrence of stubborn generalized itch, no change can be seen on the skin surface in general, just unbearable severe itch; not related to climate change, no anti-itch medication is effective. Localized itching can sometimes indicate tumors in the adjacent areas: for example, itching in the vulva is commonly associated with cervical cancer, itching around the anus suggests intestinal cancer, and itching in the nostril wall may have brain tumors. However, the severity and duration of itching are not related to tumors. Therefore, persistent itching with unknown skin cause should not be scratched, but should be identified as early as possible for timely diagnosis and treatment. In particular, people who have not suffered from skin diseases before should be reminded that when persistent and intense skin itching suddenly occurs without drug allergy, food allergy and other factors stimulation, they should go to hospital immediately for examination to exclude the possibility of diseases so as not to delay the condition.