Dry mouth and bitterness in cholecystitis can usually be cured with aggressive treatment. In cholecystitis, the gallbladder’s ability to excrete bile is weakened, which may result in bile reflux, causing the patient to experience dry mouth and bitterness. The symptoms of dry mouth and bitterness usually resolve or even disappear after treatment of cholecystitis, so cholecystitis dry mouth and bitterness can usually be cured. It is often treated by improving lifestyle, taking medication, or undergoing surgery. 1. Improve lifestyle: Patients with cholecystitis should eat a light diet and avoid barbecue, deep-fried and other high-fat foods, so as not to aggravate the burden on the gallbladder. At the same time, pay attention to the appropriate enhancement of exercise, ensure adequate sleep, drink more water, enhance their physical condition. 2. Take drugs: patients can take penicillin, levofloxacin and other antibiotic treatment, can also take ursodeoxycholic acid and other choleretic drugs to promote the recovery of cholecystitis. Because of the bile reflux caused by dry mouth patients can also take domperidone, mosapride and other pro-dynamic drugs to reduce reflux, relieve the symptoms of dry mouth and bitter mouth. 3. Surgical treatment: If the patient’s symptoms are serious and affect normal life, surgical treatment such as cholecystectomy can also be performed for radical treatment. Patients with cholecystitis are advised to consult a doctor in time and actively receive treatment. Medications should be taken strictly according to the doctor’s instructions, and should not be used on their own, so as not to delay or even aggravate the condition.