Coldness of the outer thighs and buttocks may be caused by blood deficiency and cold syncope or qi stagnation and blood stasis (blood stagnation due to lack of qi circulation), which can be relieved by taking Angelica Si-Reverse Tang or Body Pain and Blood Stasis Relieving Tang. However, the specific medication should be prescribed by a medical practitioner. 1. People with blood deficiency and cold syncope can be relieved by taking Angelica Si-Yi Tang, which has the effect of warming the meridians and dispersing cold (warming the meridians and collaterals of the human body and dispelling the cold in the body), nourishing the blood and opening up the veins, and it has a certain alleviating effect on the cold syncope of the hands and feet, or pain in the waist, femur, legs, feet, shoulders and arms, and so on. The adverse reactions and contraindications of this formula are not clear. 2. Cold thighs and buttocks caused by Qi stagnation and blood stasis can be relieved by taking Body Pain and Blood Stasis Relieving Tang, which has the efficacy of dispersing wind and activating blood (dispersing wind and evil spirits and promoting blood circulation), and clearing collaterals and relieving pain (clearing meridians and collaterals and relieving pain), and it can treat shoulder, arm, lumbar, leg, and peripheral body pain caused by paralysis of meridians and collaterals caused by blood and qi. The adverse reactions and contraindications of this formula are not known. The above drugs have some relieving effect on cold outer thighs and buttocks, but the efficacy varies from person to person, please go to regular hospitals for diagnosis and consultation in time to avoid delaying the condition.