The skull is too important for the health of the whole body, but in neurosurgery there are many patients who come to the clinic with skull defects because they have injured the skull in an accident. The cranial defect makes the whole skull unpleasant to look at, the original closed cranial environment is destroyed, the intracranial pressure is changed, and the patient suffers from a series of physical symptoms. Clinically, cranial defect will lead to dizziness and headache, patients may also have irritability, emotional irritability and other performance, and will be very insecure, long-term cranial defect without repair will cause more damage, especially if the secondary accident occurs, it is easy to injure the intracranial tissue, posing a threat to life. Cranial defects are important to every patient. In order to restore a good-looking skull shape and to rebuild a closed and complete intracranial environment, patients should go to a regular hospital for cranial repair surgery, which is a routine procedure in neurosurgery and has a history of development for thousands of years. This is a routine procedure in neurosurgery that has been developed for thousands of years. Although many local larger hospitals can usually do this surgery, it is still difficult to do it well. Especially in the skull repair surgery, the good or bad repair material and the operator’s technical operation directly affect the result of the surgery. At present, most hospitals use titanium mesh material, but titanium mesh material has many unsatisfactory aspects, such as postoperative infection rejection, cutting pain, affecting postoperative medical examination and material exposure, etc. At present, we use the new polyether ether ketone peek material to carry out skull repair surgery. peek material has more advantages than titanium mesh material, and the team has been continuously researching, constantly improving and upgrading the technology and optimizing the design of the material, and also introducing the concept of cosmetic surgery to make the result more natural and beautiful.