The treatment of chronic obstructive pulmonary disease is not fixed and is graded mainly according to the severity of the patient’s condition. It is important to note that all of these medications do not slow down the trend of declining lung function, so medication is only used to reduce symptoms, reduce complications, improve quality of life and improve health status. At present, only smoking cessation can stop the progression of the disease. As the acute exacerbation of chronic obstructive pulmonary disease is serious, it is often complicated by heart failure, respiratory failure and even pulmonary encephalopathy, therefore, once the acute exacerbation of the disease, patients should go to the hospital and be treated by a respiratory physician, and if necessary, be hospitalized. The common medications for chronic obstructive pulmonary disease are: 1, β2 adrenoceptor agonists, short-acting drugs including salbutamol aerosol, terbutaline aerosol, long-acting drugs including salmeterol, formoterol, etc., long-acting drugs only need to be inhaled twice a day. 2, anticholinergic drugs, mainly ipratropium bromide aerosol, tiotropium bromide aerosol, etc. 3, theophylline drugs: mainly aminophylline and theophylline extended-release tablets, doxorubicin 4.Glucocorticoids: fluticasone, budesonide, etc. 5.Expectorants, can be applied to patients whose sputum is not easily coughed up, mainly including aminoglutethimide hydrochloride, acetylcysteine effervescent tablets, carboxymethylstilbestrol, etc. 6.Immunomodulators: timely influenza vaccination, immunity-boosting drugs splenomycin. 7.Patients with acute exacerbation should also apply anti-inflammatory drugs. 8.Long-term home oxygen therapy, long-term home oxygen therapy can improve the quality of life and survival rate of patients, and the use of simple, patient Easy to accept, no pain. Commonly used drugs for chronic obstructive pulmonary disease are as follows: 1, combined preparation of glucocorticoids and β2 agonists: mainly used in the stable phase; 2, anticholinergic drugs: short-acting preparation of ipratropium bromide, long-acting preparation of tiotropium bromide; 3, theophylline drugs: including theophylline extended-release tablets, doxorubicin, aminophylline, etc.; 4, leukotriene receptor antagonists: such as montelukast sodium; 5, anti-IgE antibody drugs; 6, antibiotics The initial use of empirical treatment, and later select sensitive antibiotics for treatment according to the results of sputum culture that is drug sensitivity test. The specific medication should be combined with the clinical situation and guided by the doctor’s interview.