Topical treatment is the main means of eczema treatment, and topical medication is particularly important in local treatment. The topical medications for eczema are mainly glucocorticoids, and the choice of topical glucocorticoids mainly depends on the shape of the eczema lesions and the selection of appropriate topical medications. If the eczema on the back of the hand is hypertrophic and obvious, you should use medium-strength glucocorticoids, such as mometasone furoate and halometasone. If the eczema is relatively mild, no exudation, no vesicles, only erythema and papules, you can use topical glycolate lotion or combine it with a weak glucocorticoid, such as hydrocortisone butyrate, or dinaide or dexamethasone cream. If the eczema on the back of the hand is oozing and vesicular, it needs to be combined with cold wet compresses such as 3% boric acid solution, or compound eucalyptus solution for wet compresses. In addition to topical creams, local care of eczema on the back of the hand is also important, and the use of irritating topical medications should be reduced as well as good care of the hands.