The efficacy of Vinyl Estradiol Ointment is to treat diseases caused by estrogen insufficiency or deficiency. The main ingredient of Vinyl Estradiol Ointment is synthetic non-steroidal estrogen, and its effect is to supplement estrogen by being absorbed by the body through applying on the skin. It is mainly adapted to treat diseases caused by estrogen insufficiency or lack of estrogen in the body, such as atrophic vaginitis, menopausal syndromes, post-ovariectomy, primary ovarian deficiency and so on. Some side effects can exist after the application of this drug, such as irregular vaginal bleeding, uterine hypertrophy, frequent urination or painful urination. In severe cases, they can manifest as abnormal cardiac function, abnormal liver function, and hyperlipidemia. Less common side effects may manifest as gastrointestinal symptoms and mental symptoms such as dizziness. Contraindications for the application of this product include pregnant women, patients with estrogen-related tumors, abnormal vaginal bleeding that cannot exclude malignant lesions, and patients with hypertension. The application of ethinyl estradiol ointment requires the professional guidance of a clinician and should not be applied arbitrarily.