High blood glucose does not necessarily require long-term medication, depending on the condition. High blood sugar can be seen in stress hyperglycemia, prediabetes and diabetes and other pathologies. Stress hyperglycemia does not need medication; pre-diabetes is generally recommended first diet and exercise therapy, poor blood sugar control and then medication; diabetic patients with poor blood sugar control is the need for long-term medication. 1. Stress hyperglycemia: in a state of stress, such as surgery, trauma, serious infections, etc., there can be a short period of time blood glucose, general treatment of the original disease after the blood glucose can be returned to normal, do not need to take long-term medication. 2. Pre-diabetes: refers to the level of blood glucose is higher than normal but does not reach the diagnosis of diabetes standards, generally the first is a diet combined with exercise to control blood glucose, and then there is poor blood glucose control can be added to the drug therapy. 3. diabetes: diabetes is a chronic disease, generally to life-long medication. type 2 diabetes requires life-long oral medication or insulin injection; type 1 diabetes requires life-long insulin injection. High blood sugar should be found in the hospital, under the guidance of the doctor treatment, do not self-medication.