Sleeping with something pressing on your throat can be caused by swelling in the throat, reflux pharyngitis and apnea syndrome. 1. Swelling in the throat: If there is a swelling in the throat, such as an epiglottis cyst or a pharyngeal tumor, the swelling may compress the surrounding tissues during sleep, which may cause the phenomenon of feeling that there is something pressing on the throat during sleep. 2. Reflux pharyngitis: these patients usually have reflux of gastric contents, which will stimulate the mucous membrane of the patient’s throat, resulting in a foreign body sensation in the throat, especially at night when the vagus nerve is excited during sleep, the symptom may be more pronounced, so that the patient may always feel something pressing on the throat while sleeping. 3. Apnea syndrome: such patients usually have soft palate mucosal relaxation, palatine edema, or tonsillar hypertrophy, etc., when the patient sleeps, there will be a feeling of something pressing on the throat. Sleeping with the old feeling of something pressing on the throat there are other possibilities, it is recommended that patients go to the hospital in a timely manner to find out the cause of the disease, for treatment.