Side effects of taking painkillers: a. Painkillers can be taken without too much worry if taken occasionally, they can generally be metabolized normally and will not produce dependence. If the long-term symptomatic pain treatment, you should clarify the cause of the disease, to avoid excessive reliance on painkillers. Second, most painkillers have certain irritation to the gastrointestinal tract, such as aspirin, ibuprofen and acetaminophen, so when taking painkillers, you should try to choose half an hour after meals. Long-term use of painkillers is prone to acid reflux, heartburn, stomach pain and other discomforts, and some patients will also develop gastric ulcers, and serious cases will cause bleeding from the perforation of the ulcer. Third, drugs are generally metabolized by the liver and kidneys, so long-term use is likely to cause abnormal liver and kidney function, so patients with abnormal liver and kidney function should be used with caution. Allergy, some patients can be allergic after taking the drug, rash on the body, breathing difficulties, etc. Serious cases may also occur anaphylaxis. V. Discomfort such as panic, chest tightness and increased heart rate. Therefore, painkillers should be taken under the guidance of a physician to avoid self-medication, which may produce dependence or cover up the condition.