Generally, only acute hepatitis B can be self-cured. For the age of self-healing of hepatitis B, as long as it is greater than 18 years old or above, that is to say, adults, more than 90% of them can be self-healed, and a small portion of them can not be self-healed and will turn into chronic hepatitis B. Chronic hepatitis B can not be self-healed. The diagnostic criteria for acute hepatitis B and chronic hepatitis B is mainly the duration of the disease, if the duration of the disease is more than half a year, it is chronic hepatitis B. If the disease has been treated with antiviral therapy, it is chronic. Chronic hepatitis B requires antiviral treatment if indicated. Antiviral treatment requires a long-term process, usually at least four years, and some people may need to take medication for life. During the course of antiviral treatment, attention needs to be paid to monitoring liver function, hepatitis B DNA, hepatitis B five indicators and other programs to assess the condition.