Urea Vitamin E Cream can be applied to the face, but the drug is mainly used for the treatment of chapped hands and feet, and patients are advised to use the drug as prescribed by the doctor. Urea Vitamin E Cream is a compound preparation, the components include urea and vitamin E. The former can dissolve and denature the skin keratin, so that the hydration of the stratum corneum is enhanced, thus preventing the skin from drying out and cracking, and promoting the softness of the skin. The latter is an antioxidant that maintains normal nerve and muscle development and function. Urea Vitamin E cream contraindications for allergy to any of the components of the drug is prohibited, the drug to avoid contact with the eyes, so in principle can be applied to the face, but urea Vitamin E cream is mainly used for hands and feet, the treatment of chapped hands and feet or keratinized tinea cruris caused by chapped hands and feet, more than not applied to the face. Some patients using urea Vitamin E cream can appear after the skin burning sensation, rash, itching and other adverse reactions, this time should immediately wash the local drug, if necessary, should seek medical attention. Patients should follow the doctor’s instructions to use urea Vitamin E cream, avoid blindly use their own medication, so as not to affect the condition, or to induce adverse reactions.