Pyloric obstruction is mainly associated with diseases such as gastric ulcer and gastric cancer, which usually cannot be cured by themselves and need to be intervened by appropriate medical measures. 1. Gastric ulcer, chronic gastritis and other diseases can lead to ulceration of the mucosa at the pylorus. Once the ulcer is scarred, pyloric obstruction can occur. In addition, malignant tumors in the stomach can also lead to pyloric obstruction as the tumor grows. 2. Usually, pyloric obstruction caused by the above factors cannot be cured by itself, and should be intervened promptly with corresponding medical measures. (1) Gastric ulcer: Omeprazole, aluminum hydroxide and other drugs can be used under medical supervision. If necessary, the treatment of pyloric obstruction can be considered as appropriate, such as taking a large part of the stomach to be resected. (2) Gastric cancer: early gastric cancer should be mainly resected by surgery. For advanced gastric cancer patients, enteral nutritional support should be provided through nasojejunal nutritional tube. At the same time, radiotherapy and chemotherapy should be provided as prescribed by doctors. As the causes of pyloric obstruction are complicated, it is recommended to consult a doctor as soon as possible to confirm the cause of the disease and carry out treatment under the guidance of a doctor.